Understanding the 2007 Reversal

To date there have been two landmark studies in Rett research. The discovery of the gene by Huda Zoghbi and the reversal experiments by Adrian Bird which changed our thinking not only of Rett Syndrome but an entire class of childhood neurological disorders.

On June 27, 2006 at the 7th Annual Rett Syndrome Symposium organized by Monica Coenraads then Director of Research of the Rett Syndrome Research Foundation, Adrian Bird presented his dramatic data showing reversal of Rett symptoms in adult male and female mice. On February 8, 2007 the results were published in Science and received wide national and international attention.

The following videos will help you understand the key points of this work.