The reversal experiments changed everything.

On February 8, 2007 the journal Science announced astonishing and unexpected results with the publication of a paper entitled Reversal of Neurological Defects in a Mouse Model of Rett Syndrome, by Adrian Bird,  Ph.D. of the University of Edinburgh.

Until this point research was focused on diagnosis and prevention, or at best, a therapy that could be initiated during the small window of opportunity before symptoms in a baby begin to manifest. Professor Bird’s work has now made the reversal of full-blown symptoms a tangible possibility.

The portfolio of projects that RSRT is funding represent the next logical steps in a focused effort to treat and cure Rett Syndrome.

RSRT will quickly prioritize resources as new data emerges from our projects as well as ongoing work in labs around the world.

Banner image - Mouse neurons from the nodose ganglia (part of the vagus nerve). MECP2 stains green. Photography courtesy of David Katz/Journal of Neuroscience.